A percentage of the money generated from the sale of exhibition spaces will be going straight to the charity, which gives care and support to patients and their families in Bath and north east Somerset and parts of Wiltshire.
The Dorothy House team will also be in attendance at the show helping to facilitate key activities and running some fundraising activities.
The business show will take place on Wednesday, March 21 at The Springfield Community Centre, Corsham, offering networking opportunities and the chance to develop knowledge and skills at four workshops.
Stuart Pearce, president of Corsham Chamber of Commerce, said: "Throughout the planning process for the Corsham Business Show we wanted to find a local charity that we could help raise awareness of, along with supporting their fundraising needs.
"We were delighted when Dorothy House Hospice accepted our invitation to join us on the big day. They are a wonderful charity, seamlessly integrated into the local community and tirelessly supporting families in need day in and day out.”
For more information, or to book an exhibition space, visit www.corshambusinessshow.co.uk